1. 毕业设计（论文）的内容和要求
内容：加巴喷丁（gabapentin，GBP）是一种新型的抗癫痫药物，近年来的使用量越来越多 [1,2]。
然而，GBP不容易被人体内代谢，几乎全部以原药的形式通过尿液排出体外 [3]。
因此，GBP在水环境中被频繁检出 [4-6]。
2. 参考文献
[1] Lai F Y, Ort C, Gartner C, et al. Refining the estimation of illicit drug consumptions from wastewater analysis: Co-analysis of prescription pharmaceuticals and uncertainty assessment[J]. Water Research, 2011, 45(15): 4437-4448.[2] Herrmann M, Menz J, Olsson O, et al. Identification of phototransformation products of the antiepileptic drug gabapentin: Biodegradability and initial assessment of toxicity[J]. Water Research, 2015, 85: 11-21.[3] Panayiotopoulos C P. Atlas of epilepsies[M].London ; New York: Springer, 2010.[4] Gurke R, Rossler M, Marx C, et al. Occurrence and removal of frequently prescribed pharmaceuticals and corresponding metabolites in wastewater of a sewage treatment plant[J]. Science Of the Total Environment, 2015, 532: 762-770.[5] Kasprzyk-Hordern B, Dinsdale R M, Guwy A J. The removal of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs during wastewater treatment and its impact on the quality of receiving waters[J]. Water Research, 2009, 43(2): 363-380.[6] Henning N, Kunkel U, Wick A, et al. Biotransformation of gabapentin in surface water matrices under different redox conditions and the occurrence of one major TP in the aquatic environment[J]. Water Research, 2018, 137: 290-300.[7] Almeida A, Calisto V, Domingues M R M, et al. Comparison of the toxicological impacts of carbamazepine and a mixture of its photodegradation products in Scrobicularia plana[J]. Journal Of Hazardous Materials, 2017, 323: 220-232.
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