1. 毕业设计（论文）的内容和要求
本次论文的完成主要有以下要求：查阅相关文献资料，能够读懂英文文献；综合文献中的实验方法，设计与课题相关的条件实验；开展各个不同的条件实验，在实际操作过程中要能够分析并解决突发问题，能够对不同的实验结果进行分析对比；通过红外、核磁光谱对目标产物进行鉴定，能够对谱图进行分析；最后完成撰写本课题论文的任务。
2. 参考文献
[1]Design, synthesis, and immunological evaluation of a multicomponent construct based on a glycotripeptoid core comprising B and T cell epitopes and a Toll-like Receptor 7 agonist that elicit potent immune responses；[2]Facile syntheses of functionalized toll-like receptor 7 agonists；[3]Synthesis and Immunological Characterization of Toll-Like Receptor 7 Agonistic Conjugates；[4]A conjugate of octamer-binding transcriptionfactor 4 and toll-like receptor 7 agonist preventsthe growth and metastasis of testis embryoniccarcinoma；[5]Weterings, J. J.; Khan, S.; van der Heden van Noort, G. J.; Melief, C. J. M.; Overkleeft, H. S.; van der Burg, S. H.;Ossendorp, F.; van der Marel, G. A.; Filippov, D. V. Bioorg. Med. Chem. Lett. 2009, 19, 2249-2251.[6] Hirota, K.; Kazaoka, K.; Sajiki, H. Bioorg. Med. Chem. 2003, 11, 2715-2722.[7] Hirota, K.; Kazaoka, K.; Niimoto, I.; Sajiki, H. Org. Biomol. Chem. 2003, 1, 1354-1365.[8] Boquin, J. R. Ph.D. Dissertation, Baylor University, Waco, TX, May 2010.[9] Wu, C. C. N.; Hayashi, T.; Takabayashi, K.; Sabet, M.; Smee, D. F.; Guiney, D. D.; Cottam, H. B.; Carson, D. A.Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 3990-3995.[10] (a) New, O. M.; Dolphin, D. Eur. J. Org. Chem. 2009, 2675-2686. (b) Landi, F.; Johansson, C. M.; Campopiano, D. J.;Hulme, A. N. Org. Biomol. Chem. 2010, 8, 56-59.[11] El-Faham, A.; Albericio, F. J. Pept. Sci. 2010, 16, 6-9.[12] Marom, H.; Miller, K.; Bechor-Bar, Y.; Tsarfaty, G.; Satchi-Fainaro, R.; Gozin, M. J. Med. Chem. 2010, 53, 6316-6325.
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