1. 毕业设计（论文）的内容和要求
纳米二氧化硅粒径小、比表面积大、生物相容性好，是应用最广泛的无机纳米材料。
纳米二氧化硅表面有大量活泼的羟基，使得对其进一步的功能化改性成为可能。
直链高碳醇来源于脂肪酸，是绿色可再生资源，成本低廉，用于改性二氧化硅颗粒可制得疏水二氧化硅，但是现今的改性工艺常需要高温高压，反应要求较高。
2. 参考文献
[1] Brhwiler, Dominik. Postsynthetic functionalization of mesoporous silica[J]. Nanoscale, 2010, 2(6):887-0.[2] Lee A W H , Gates B D . Rapid Covalent Modification of Silicon Oxide Surfaces through Microwave-Assisted Reactions with Alcohols[J]. Langmuir, 2016, 32(29):7284-7293.[3] Salim M A , Misran H , Othman S Z , et al. Synthesis and Characterizations of SiO2-Ag Core-Shell Nanostructure Using Fatty Alcohols as Surface Modifiers[J]. Applied Mechanics and Materials, 2015, 773-774:199-203.[4] Jesionowski T , Jolanta urawska, Krysztafkiewicz A , et al. Physicochemical and morphological properties of hydrated silicas precipitated following alkoxysilane surface modification[J]. Applied Surface Science, 2003, 205(1):212-224.[5] Dickinson E , Ettelaie R , Kostakis T , et al. Factors Controlling the Formation and Stability of Air Bubbles Stabilized by Partially Hydrophobic Silica Nanoparticles[J]. Langmuir, 2004, 20(20):8517-8525.[6] Fukaya N , Yamashita H , Haga H , et al. Microwave-assisted organic functionalization of silica surfaces: Effect of selectively heating silylating agents[J]. Journal of Organometallic Chemistry, 2011, 696(4):825-828.[7] Lin J , Chen H , Yuan Y , et al. Mechanochemically conjugated PMHS/nano-SiO2 hybrid and subsequent optimum grafting density study[J]. Applied Surface Science, 2011, 257(21):9024-9032.[8] Guidotti B R , Herzog E , Bangerter F , et al. Modification of SiO2Surfaces by Reaction with Acetals, Ketals, Orthoesters, and Orthocarbonates[J]. Journal of Colloid Interface Science, 1997, 191(1):209-215.[9] Fuji M，Takei T， Watanabe T， et al． Wettability of Fine Silica Powder Surfaces Modified with Several Normal Alcohols[J].Colloids and Surfaces A: Physicochemical and Engineering Aspects， 1999， 154(1) :13- 24．[10] An D , Wang Z , Zhao X , et al. A new route to synthesis of surface hydrophobic silica with long-chain alcohols in water phase[J]. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2010, 369(1-3):218-222.
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