1. 毕业设计（论文）的内容和要求
1、查阅相关文献，掌握文献的归纳总结，翻译一篇与课题相关的文章，写文献综述；
2、理解并掌握抗哮喘药沙美特罗杂质的结构、性质、合成方法及其基本原理；
3、掌握相关表征手段及数据处理软件，学会分析实验结果中存在的问题；
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2. 参考文献
[1] Francis M. Dean, G. Antonio Herbin, David A. Matkin, Anthony W. Price, and Malcolm L. Robinson, Spirans. Part 13.' The Synthesis and Orientation of Spirans related to Abel's Ketone (Naphtho[P,I -b]furan-2(1H)-spiro-1'(2'H)-naphthalen-2'- one).
[2] Sajal Kumar Das,Gautam Panda,Vinita Chaturvedi,Y. S. Manju,Anil K. Gaikwad and Sudhir Sinha, Bioorganic Medicinal Chemistry Letters 17 (2007) 55865589.
[3] Diane M. Coe, Rossana Perciaccante and Panayiotis A. Procopiou. Potassium trimethylsilanolate induced cleavage of 1,3-oxazolidin-2-and 5-ones, and application to the synthesis of (R )-salmeterol. Org. Biomol. Chem., 2003, 1, 11061111.
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