1. 毕业设计（论文）的内容和要求
1、查阅相关文献，掌握文献的归纳总结，翻译一篇与课题相关的文章，写文献综述；2、理解并掌握含氟侧链芳香胺的结构、性质、制备方法；3、掌握相关数据处理软件，学会实验数据处理；4、保持实验室整洁，培养良好的卫生习惯；5、按科技论文规范书写毕业论文，做好PPT，并认真准备答辩。
要求：课题理解课题，通过阅读文献，在研究生的帮助下，提出自己的思路，并进行独立实验，经过系统的实验得出相关数据，能运用数据处理软件进行数据处理，最终得出关于合成含氟侧链的芳香胺的研究，并结合结论反思整个实验过程。
2. 参考文献
[1] William R. Jr. Dolbier, Fluorine chemistry at the millennium [J].J. Fluorine Chem.2005,126,157-163[2]OHagan,C.Schaffrath,S.L.Cobb,J.T.G.Hamilton,C.D.Murphy,Biochemistry:Biosynthesis of an organofluorine molecule[J].Nature 2002,416,279[3] Peer Kirsch. Modern Fluoroorganic Chemistry [M]. Weinheim ,Wiley-VCH, 2004.1-21[4] C.Isanbor, D.O'Hagan, Fluorine in medicinal chemistry: A review of anti-cancer agents [J].J. Fluorine Chem. 2006,127, 303[5] William K.Hagmann. The Many Roles for Fluorine in Medicinal Chemistry[J]. J. Med. Chem.. 2008, 51 (15): 43594369[6] 卿凤翎, 邱小龙编. 有机氟化学[M]，科学出版社，2007.[7] 李楠，刘伟军，龚流柱. 手性有机小分子催化最新进展[J].化学进展, 2006, 22, 1362-1379.[8] Special Issue: Asymmetric Organocatalysis[J].Acc.Chem.Res.2004,37,487[9] C. Anaya de Parrodi, E. Juaristi, Chiral 1,2-Amino Alcohols and 1,2-Diamines Derived from Cyclohexene Oxide: Recent Applications in Asymmetric Synthesis[J]. Synlett 2006, 17, 26992715 [10] K. Yamada, S. J. Harwood, H. Grger, M. Shibasaki, The First Catalytic Asymmetric Nitro-Mannich-Type Reaction Promoted by a New Heterobimetallic Complex[J].Angew.Chem. Int. Ed. 1999, 38, 35043506.[11] K. Yamada, G. Moll, M. Shibasaki, The First Enantioselective and Diastereoselective Catalytic Nitro-Mannich Reaction: A New Entry to Chiral Vicinal Diamines[J]. Synlett 2001,SI: 980982.[12]N. Nishiwaki, K. R. Knudsen, K. V. Gothelf, K. A. Jrgensen, Catalytic Enantioselective Addition of Nitro Compounds to Imines-A Simple Approach for the Synthesis of Optically Active b-Nitro-a-Amino Esters[J].Angew. Chem. Int. Ed. 2001, 40, 29922995
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