镍催化的烯烃氢氰化反应研究任务书

 2022-02-10 06:02

全文总字数:4284字

1. 毕业设计(论文)的内容和要求

腈和烯烃是在材料的制备、药品、化妆品和农用化学品中具有互补反应活性的重要合成中间体。

在这里,我们报道了一个镍催化的转移氢氰化反应之间的广泛范围(60个例子)的烷基腈和烯烃。

这一策略不仅克服了传统方法中使用HCN所带来的毒性挑战,而且包含了独特的化学进展,包括反氢氰化和反马氏区域选择性。

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2. 实验内容和要求

利用镍催化无HCN的烷基腈和烯烃之间的可逆转移氢氰化反应,并可对产物选择性进行可调控制,(避免在实验室中使用挥发性和危险试剂)实现烯烃可逆的氢化功能化,再开发其在医药等方面的可能应用。

3. 参考文献

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4. 毕业设计(论文)计划

2021.3.8前,查阅文献,确定毕业设计(论文)题目,实验前期准备;2021.5.20前,进行课题的实验、设计、调研及结果的处理与分析等,完成毕业设计说明书或论文写作、修改和完善论文;2021.6,进行毕业设计(论文)答辩

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