1. 毕业设计（论文）的内容和要求
（1）掌握文献查阅的一般方法，学会在中国期刊网、Web of Science科学引文索引、Springer Link电子期刊、Elsevier SDOS电子期刊等检索资源上查阅关于红曲霉发酵产色素等的相关文献，并对红曲霉发酵培养有全面了解。
（2）文献阅读及综述：阅读与课题相关的中英文文献，了解国内外的研究动态，撰写文献综述。
（3）明确实验任务，拟定实验方案：根据所查阅文献的内容，确定研究内容及方案，拟定科学可行的研究计划。
2. 参考文献
[1] Vendruscolo F, Bhler R M M, de Carvalho J C, et al. Monascus: a reality on the production and application of microbial pigments[J]. Applied biochemistry and biotechnology, 2016, 178(2): 211-223.[2] Vendruscolo F, Schmidell W, Moritz D E, et al. Isoelectric point of amino acid: Importance for monascus pigment production[J]. Biocatalysis and Agricultural Biotechnology, 2016, 5: 179-185.[3] Hu Y, Zhou Y, Mao Z, et al. NAD -dependent HDAC inhibitor stimulates Monascus pigment production but inhibit citrinin[J]. AMB Express, 2017, 7(1): 166.[4] Srianta I, Zubaidah E, Estiasih T, et al. Comparison of Monascus purpureus growth, pigment production and composition on different cereal substrates with solid state fermentation[J]. Biocatalysis and agricultural biotechnology, 2016, 7: 181-186.[5] Liu J, Guo T, Luo Y, et al. Enhancement of Monascus pigment productivity via a simultaneous fermentation process and separation system using immobilized-cell fermentation[J]. Bioresource technology, 2019, 272: 552-560.[6] Wang B, Zhang X, Wu Z, et al. Biosynthesis of Monascus pigments by resting cell submerged culture in nonionic surfactant micelle aqueous solution[J]. Applied microbiology and biotechnology, 2016, 100(16): 7083-7089.[7] Liu L, Wu S, Wang W, et al. Sulfonation of Monascus pigments to produce water-soluble yellow pigments[J]. Dyes and Pigments, 2020, 173: 107965.[8] Chen G, Huang T, Bei Q, et al. Correlation of pigment production with mycelium morphology in extractive fermentation of Monascus anka GIM 3.592[J]. Process Biochemistry, 2017, 58: 42-50.[9] Patrovsky M, Sinovska K, Branska B, et al. Effect of initial pH, different nitrogen sources, and cultivation time on the production of yellow or orange Monascus purpureus pigments and the mycotoxin citrinin[J]. Food science s Spent Grain[J]. Foods, 2019, 8(5): 161.[30] Wang M, Huang T, Chen G, et al. Production of water-soluble yellow pigments via high glucose stress fermentation of Monascus ruber CGMCC 10910[J]. Applied microbiology and biotechnology, 2017, 101(8): 3121-3130.[31] Huang T, Wang M, Shi K, et al. Metabolism and secretion of yellow pigment under high glucose stress with Monascus ruber[J]. AMB Express, 2017, 7(1): 79.[32] Huang Z R, Zhou W B, Yang X L, et al. The regulation mechanisms of soluble starch and glycerol for production of azaphilone pigments in Monascus purpureus FAFU618 as revealed by comparative proteomic and transcriptional analyses[J]. Food research international, 2018, 106: 626-635.[33] Shi K, Chen G, Pistolozzi M, et al. Improved analysis of Monascus pigments based on their pH-sensitive Uv-Vis absorption and reactivity properties[J]. Food Additives edible oil two-phase system[J]. Bioprocess and biosystems engineering, 2016, 39(11): 1785-1791.[49] Jian W, Sun Y, Wu J Y. Improving the water solubility of Monascus pigments under acidic conditions with gum arabic[J]. Journal of the science of food and agriculture, 2017, 97(9): 2926-2933.[50] Tian X, Tang R, Chen G, et al. Separation of Monascus pigments from extractive fermentation broth with a high concentration of triton X-100[J]. Separation Science and Technology, 2018, 53(16): 2601-2611.
