运用液态芯片法检测胃癌患者血清中CRP的含量任务书

 2021-10-15 09:10

1. 毕业设计(论文)的内容和要求

毕业设计(论文)是本科专业人才培训计划中最后一个综合性教学环节,是培养学生工程时间能力、理论研究能力和创新意识的严重途径,是学生毕业及学位资格认定的重要依据。

本课题是建立在分子生物学和免疫学基础上的一种新型蛋白质检测手段,意在研究与胃癌相关的肿瘤标志物CRP,这在肿瘤的诊断、监测及预后等方面有着重要的临床价值。

通过本实验的进行,主要目的是培养学生综合运用所学理论知识和基本技能解决实际问题的能力,初步具有从事科学研究能力。

2. 参考文献

[1] Agrawal A,Shrive AK,Greenhough TJ,et a1.Topology andstructure of the Clq-binding site on C-reactive protein[J].J Immunol,2001,166(6):3998-4004.[2]Baek JE,Chang jw,Min WK,et a1.Serum high-sensitivity C-reactive protein is not increased in patients with IgA nephropathy[J].Nephron Clin Pract,2008,108(1):35-40.[3]Sabatine MS,Morrow DA,Jablonski KA,et a1.Prognostic significance of the Centers for Disease Control/American Heart Association high sensitivity C reactive protein cut points for eardiovascular and other outcomes in patients with stable coronary artery disease[J].Circulation,2007,115(12):1528-1536.[4]Soinio M,Marniemi J,Laakso M,et a1.High-sensitivity C-reac-tive protein and coronary heart disease mortality in patients with type 2 diabetes:a 7-year follow-up study[J].Diabetes Care,2006,29(2):329-333.[5]Villacorta H,Masetto AC,Mesquita ET.C-reactive protein:aninflammatory marker with prognostic value in patients with decompensated heart failure EJ3.Arq Bras Cardiol,2007,88(5):585-589.[6]Arcari A,Zito F,Di Castelnuovo A,et a1.C reactive protein and itsdeterminants in healthy men and women from European regions atdifferent risk of coronary disease. MMIDIET Project[J].2008,6(3):436-443.

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