铁/硫-催化氧化还原缩合反应制备2-芳基苯并恶唑任务书

 2021-11-05 07:11

1. 毕业设计(论文)的内容和要求

1.文献查阅掌握文献查阅的一般方法,学会使用计算机在中国期刊网、维普数据库、超星数字图书馆、美国化学学会(ACS)数据库、Elseiver、CA、EI和SCI等检索资源上查阅关于2-芳基苯并恶唑的相关文献。

2.文献阅读及综述阅读与课题相关的外文及中文文献,了解国内外的研究动态,撰写文献综述。

3.明确实验任务,拟定实验方案根据所查阅文献的内容,确定实验内容及方案,拟定科学可行的研究计划。

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2. 参考文献

[1] Turchi, I. J.; Dewar, M. J. S. Chemistry of oxazoles [J]. Chem. Rev. 1975, 75, 389-437; [2] Boyer, J.; Arnoult, E.; Mdebielle, M.; Guillemont, J.; Unge, J.; Jochmans, D. Difluoromethylbenzoxazole pyrimidine thioether derivatives: A novel class of potent non-nucleoside HIV-1 reverse transcriptase inhibitors [J]. J. Med. Chem. 2011, 54, 7974-7985; [3] Rajasekhar, S.; Maiti, B.; Chanda, K. A decade update on benzoxazoles, a privileged scaffold in synthetic organic chemistry [J]. Synlett 2017, 28, 521-541;[4] Wang, X.; Li, P.; Yuan, X.; Lu, S. Synthesis of symmetrical 1,3-diarylureas by sulfur-catalyzed carbonylation in ionic liquids [J]. J. Mol. Catal. A, 2006, 255, 25-27; [5] Nguyen, T. B.; Ermolenko, L.; Almourabit, A. Iron sulfide catalyzed redox/condensation cascade reaction between 2-amino/hydroxy nitrobenzenes and activated methyl groups: A straightforward atom economical approach to 2-hetaryl-benzimidazoles and -benzoxazoles [J]. J. Am. Chem. Soc. 2013, 135, 118-121; [6] Nguyen, T. B.; Le Bescont, J.; Ermolenko, L.; Almourabit, A. Cobalt- and iron-catalyzed redox condensation of o-substituted nitrobenzenes with alkylamines: A step- and redox-economical synthesis of diazaheterocycles [J]. Org. Lett. 2013, 15, 6218-6221; [7] Nguyen, T. B.; Ermolenko, L.; Corbin, M.; Al-Mourabit, A. Fe/S-catalyzed decarboxylative redox condensation of arylacetic acids with nitroarenes [J]. Org. Chem. Front. 2014, 1, 1157-1160; [8] Nguyen, T. B.; Ermolenko, L.; Al-Mourabit, A. Sodium sulfide: A sustainable solution for unbalanced redox condensation reaction between o-nitroanilines and alcohols catalyzed by an iron-sulfur system [J]. Synthesis 2015, 47, 1741-1748;[9] Nguyen, T. B.; Nguyen, L. P. A.; Nguyen, T. T. T. Sulfur-catalyzed oxidative coupling of dibenzyl disulfides with amines: Access to thioamides and aza heterocycles [J]. Adv. Synth. Catal. 2019, 361, 1787-1791.[10] Gan, H. S8-mediated cyclization of 2-hydroxy/amino anilines with arylacetylene: Approach to benzoxazoles and benzimidazoles [J]. ChemistrySelect, 2019, 4, 8598-8601; [11] Gan, H.; Yang, D. S8-mediated decarboxylative cyclization of 2-nitrophenols with arylacetic acid: Synthesis of benzoxazoles [J]. J. Saudi Chem. Soc. 2019, 23, 809-816; [12] Gan, H. Facile preparation of benzoxazoles from S8-promoted cyclization of 2-nitrophenols with arylmethyl chloride [J]. ChemistrySelect, 2019, 4, 2858-2860; [13] Gan, H.; Miao, D.; Pan, Q.; Hu, R.; Li, X.; Han, S. S8-mediated cyclization of 2-aminophenols/thiophenols with arylmethyl chloride: approach to benzoxazoles and benzothiazoles [J]. Chem. Asian J. 2016, 11, 1770-1774; [14] Gan, H. Iron/S8-catalyzed redox condensation of o-nitroarenes with arylmethyl chloride: synthesis of benzimidazoles and benzothiazoles [J]. Asian J. Org. Chem. 2016, 5, 1111-1114.

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