硫化铜纳米颗粒光热性能探索任务书

 2021-10-24 03:10

1. 毕业设计(论文)的内容和要求

毕业设计的内容:纳米材料的快速发展是新材料科学发展的一项重要标志,其在纳米尺度下展示出的新结构,新效应以及新现象被不断的应用于很多领域。

纳米材料的调控合成是纳米材料科技发展的重要环节,也是其在各个领域应用的基础。

本设计论文将以无机半导体硫化铜作为主要研究对象,利用水热合成作为主要手段,研究不同合成条件下硫化铜纳米材料的形貌尺寸等;对合成的硫化铜进行一系列的表征及性能测试,分析其光热转化效率,并探究其在生物医学领域如药物装载以及光热治疗等中的应用。

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2. 参考文献

1.Zha Z, Wang S, Zhang S, et al. Targeted delivery of CuS nanoparticles through ultrasound image-guided microbubble destruction for efficient photothermal therapy[J]. Nanoscale, 2013, 5(8): 3216-3219.2. Liu X, Li B, Fu F, et al. Facile synthesis of biocompatible cysteine-coated CuS nanoparticles with high photothermal conversion efficiency for cancer therapy[J]. Dalton Transactions, 2014, 43(30): 11709-11715.3. Zhang C, Fu Y Y, Zhang X, et al. BSA-directed synthesis of CuS nanoparticles as a biocompatible photothermal agent for tumor ablation in vivo[J]. Dalton Transactions, 2015, 44(29): 13112-13118.4. Shi H, Yan R, Wu L, et al. Tumor-targeting CuS nanoparticles for multimodal imaging and guided photothermal therapy of lymph node metastasis[J]. Acta biomaterialia, 2018, 72: 256-265.5. Yi X, Yang K, Liang C, et al. Imaging‐Guided Combined Photothermal and Radiotherapy to Treat Subcutaneous and Metastatic Tumors Using Iodine‐131‐Doped Copper Sulfide Nanoparticles[J]. Advanced Functional Materials, 2015, 25(29): 4689-4699.6. Peng S, He Y, Er M, et al. Biocompatible CuS-based nanoplatforms for efficient photothermal therapy and chemotherapy in vivo[J]. Biomaterials science, 2017, 5(3): 475-484.7. Liang L, Peng S, Yuan Z, et al. Biocompatible tumor-targeting nanocomposites based on CuS for tumor imaging and photothermal therapy[J]. RSC advances, 2018, 8(11): 6013-6026.8. Hu X, Li L, Lu Y, et al. Multifunctional CuS nanocrystals for inhibiting both osteosarcoma proliferation and bacterial infection by photothermal therapy[J]. Journal of Nanoparticle Research, 2017, 19(9): 295.9. Chen G, Ma B, Wang Y, et al. CuS-based theranostic micelles for NIR-controlled combination chemotherapy and photothermal therapy and photoacoustic imaging[J]. ACS applied materials interfaces, 2017, 9(48): 41700-41711.10. Li N, Sun Q, Yu Z, et al. Nuclear-targeted photothermal therapy prevents cancer recurrence with near-infrared triggered copper sulfide nanoparticles[J]. ACS nano, 2018, 12(6): 5197-5206.

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