1. 毕业设计（论文）的内容和要求
本课题提出以天然高分子如透明质酸、海藻酸等为主体原料，通过儿茶酚与铂离子的金属配位作用，在凝胶化的同时，也同步实现了药物的负载，从而一步构建负载顺铂药物的金属配位聚合物水凝胶。
儿茶酚为配位体，通过配位体和金属铂离子间的配位相互作用，连接形成了三维网状结构，一步实现负载顺铂药物的金属配位聚合物水凝胶的制备。
通过将儿茶酚配位体修饰到天然高分子如透明质酸或海藻酸的主链上，为其与金属铂离子进行配位作用提供了交联位点；通过可逆的不稳地的金属配位作用，配位键的解离可引发水凝胶材料的降解且同时能够实现顺铂药物的释放。
2. 参考文献
根据毕业要求指点10.2，毕设期间要进行研究现状调查与总结，要求在开题报告及毕业设计（论文）中涉及的英文文献不少于20篇，其中近5年不少于8篇，英文文献不少于5篇。
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