1. 毕业设计（论文）的内容和要求
通过文献综述一方面了解含氮杂环及硝基芳烃类化合物其生物活性及药物价值，并找到它的合成方法；另一方面查阅涉及钌催化的远程间位碳氢功能化反应的这类文献，归纳反应体系。
2. 参考文献
1 (a) J. Yamaguchi, A. D. Yamaguchi and K. Itami, Angew.Chem., Int. Ed., 2012, 51, 89609009; (b) J. Schranck, A. Tliliand M. Beller, Angew. Chem., Int. Ed., 2014, 53, 94269428;(c) S. De Sarkar, Angew. Chem., Int. Ed., 2016, 55, 1055810560.2 (a) K. M. Engle, T.-S. Mei, M. Wasa and J.-Q. Yu, Acc. Chem.Res., 2012, 45, 788802; (b) L. Ackermann, Acc. Chem. Res.,2014, 47, 281295; (c) M. Moselage, J. Li and L. Ackermann,ACS Catal., 2016, 6, 498525.3 (a) R. Sharma, K. Thakur, R. Kumar, I. Kumar andU. Sharma, Catal. Rev.: Sci. Eng., 2015, 57, 345405;(b) J. Yang, Org. Biomol. Chem., 2015, 13, 19301941.4 D. Leow, G. Li, T.-S. Mei and J.-Q. Yu, Nature, 2012, 486,518522.5 (a) M. Bera, A. Modak, T. Patra, A. Maji and D. Maiti, Org.Lett., 2014, 16, 57605763; (b) M. Bera, A. Maji, S. K. Sahooand D. Maiti, Angew. Chem., Int. Ed., 2015, 54, 85158519;(c) A. Maji, B. Bhaskararao, S. Singha, R. B. Sunoj andD. Maiti, Chem. Sci., 2016, 7, 31473153; (d) T. Patra,R. Watile, S. Agasti, T. Naveen and D. Maiti, Chem.Commun., 2016, 52, 20272030.6 (a) X.-C. Wang, W. Gong, L.-Z. Fang, R.-Y. Zhu, S. Li,K. M. Engle and J.-Q. Yu, Nature, 2015, 519, 334338;(b) Z. Dong, J.-C. Wang and G.-B. Dong, J. Am. Chem. Soc.,2015, 137(18), 5887; (c) J. Han and Y.-S. Zhao, Chem.Commun., 2016, 52, 6903.7 (a) O. Saidi, J. Marafie, A. E. Ledger, P. M. Liu,M. F. Mahon, G. Kociok-Kohn, M. K. Whittlesey andC. G. Frost, J. Am. Chem. Soc., 2011, 133, 19298;(b) A. J. Paterson and C. G. Frost, Chem. Commun., 2015, 51,12807.8 (a) L. Ackermann, N. Hofmann and R. Vicente, Org. Lett.,2011, 13, 1875; (b) N. Hofmann and L. Ackermann, J. Am.Chem. Soc., 2013, 135(15), 5877; (c) J. Li and L. Ackermann,J. Am. Chem. Soc., 2015, 137(43), 13894.9 C. J. Teskey and M. F. Greaney, Angew. Chem., Int. Ed., 2015,54, 11677.10 Q.-Z. Yu and J.-H. Huang, Angew. Chem., Int. Ed., 2015, 54,15284.11 N. Ono, The Nitro Group in Organic Synthesis, Wiley-VCH,New York, 2001.12 (a) G. A. Olah, Acc. Chem. Res., 1971, 4, 240; (b) H. Feuer andA. T. Nielson, Nitro Compounds: Recent Advances in Synthesisand Chemistry, VCH, Weinheim, 1990; (c) A. G. M. Barrettand G. G. Graboski, Chem. Rev., 1986, 86, 751.13 Z. Fan, J. Ni and A. Zhang, J. Am. Chem. Soc., 2016, 138,84708475.14 (a) S. Miwatashi, Y. Arikawa, E. Kotani, M. Miyamoto,K. Naruo, H. Kimura, T. Tanaka, S. Asahi and S. Ohkawa,J. Med. Chem., 2005, 48, 5966; (b) Y. Choi, Y. Kawazoe,K. Murakami, H. Misawa and M. Uesugi, J. Biol. Chem.,2003, 278, 7320; (c) J. Lee, S. J. Kim, H. Choi, Y. H. Kim,I. T. Lim, H. Yang, C. S. Lee, H. R. Kang, S. K. Ahn,S. K. Moon, D.-H. Kim, S. Lee, N. S. Choi and K. J. Lee,J. Med. Chem., 2010, 53, 6337; (d) T. Suzuki, S. Hisakawa,Y. Itoh, N. Suzuki, K. Takahashi, M. Kawahata,K. Yamaguchi, H. Nakagawa and N. Miyata, Bioorg. Med.Chem. Lett., 2007, 17, 4208; (e) M. S. Alam, L. Liu, Y.-E. Leeand D.-U. Lee, Chem. Pharm. Bull., 2011, 59, 568;(f ) D. Zwilling, S.-Y. Huang, K. V. Sathyasaikumar,F. M. Notarangelo, P. Guidetti, H.-Q. Wu, J. Lee, J. Truong,Y. Andrews-Zwilling, E. W. Hsieh, J. Y. Louie, T. Wu,K. Scearce-Levie, C. Patrick, A. Adame, F. Giorgini,S. Moussaoui, G. Laue, A. Rassoulpour, G. Flik, Y. Huang,J. M. Muchowski, E. Masliah, R. Schwarcz andP. J. Muchowski, Cell, 2011, 145, 863.15 (a) J. Haemmerle, M. Schnuerch, N. Iqbal, M. D. Mihovilovicand P. Stanetty, Tetrahedron, 2010, 66, 80518059;(b) M. Schnuerch, J. Haemmerle, M. D. Mihovilovic andP. Stanetty, Synthesis, 2010, 837843; (c) S. Kirchberg, S. Tani,K. Ueda, J. Yamaguchi, A. Studer and K. Itami, Angew. Chem.,Int. Ed., 2011, 50, 23872391; (d) J. Haemmerle, M. Schnuerchand P. Stanetty, Synlett, 2007, 29752978.16 (a) Y. Ping, Z. Chen, Q. Ding and Y. Peng, Synthesis, 2017,49, 20152024; (b) L. Zhang, Z. Liu, H. Li, G. Fang,B.-D. Barry, T. A. Belay, X. Bi and Q. Liu, Org. Lett., 2011,13, 65366539; (c) C. S. Azad and A. K. Narula, RSC Adv.,2015, 5, 100223100227.17 (a) Z. Fan, J. Li, H. Lu, D.-Y. Wang, C. Wang, M. Uchiyamaand A. Zhang, Org. Lett., 2017, 19, 31993202; (b) Z. Fan,H. Lu and A. Zhang, J. Org. Chem., 2018, 83, 32453251.18 (a) Y.-K. Liu, S.-J. Lou, D.-Q. Xu and Z.-Y. Xu, Chem. Eur. J.,2010, 16, 1359013593; (b) G. G. Pawar, A. Brahmanandanand M. Kapur, Org. Lett., 2016, 18, 448451.19 (a) V. R. Sabbasani and D. Lee, Org. Lett., 2013, 15, 39543957; (b) J. Sun, J.-K. Qu, Y.-N. Wu, W.-J. Hao, C. Guo, G. Li,S.-J. Tu and B. Jiang, Org. Lett., 2017, 19, 754757.
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