电激发N自由基引发杂环远程迁移任务书

 2021-10-25 09:10

1. 毕业设计(论文)的内容和要求

随着传统化学及传统化学试剂带来的污染越来越严重,寻求更加绿色环保、经济安全的新颖化学手段或化学试剂受到了越来越多的重视。

电化学利用绿色的电能起到高效氧化还原的作用可替代传统的高污染、高危险性的氧化剂与还原剂。

本课题寻求以电催化的方法,寻求更加环保、绿色的反应进行Smiles型迁移反应,构建具有丰富生物活性的含N化合物,其在合成化学及药物化学中均具有重要的意义。

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2. 参考文献

1.Steckhan, E., Arns, T., Heineman, W. R., Hilt, G., Hoormann, D., Jorissen, J., Kroner, L., Lewall, B., and Putter, H. (2001). Environmental protection and economization of resources by electroorganic and electroenzymatic syntheses. Chemosphere 43, 63-73.2.Frontana-Uribe, B. A., Little, R. D., Ibanez, J. G., Palma, A., and Vasquez-Medrano, R. (2010). Organic electrosynthesis: a promising green methodology in organic chemistry. Green Chem. 12, 2099-2119.3.Nguyen, B. H., Redden, A., and Moeller, K. D. (2014). Sunlight, electrochemistry, and sustainable oxidation reactions. Green Chem. 16, 69-72.4.Francke, R., and Little, R. D. (2014). Redox catalysis in organic electrosynthesis: basic principles and recent developments. Chem. Soc. Rev. 43, 2492-2521.5.Zhang, P., Sheng, X., Chen, X., Fang, Z., Jiang, J., Wang, M., Li, F., Fan, L., Ren, Y., Zhang, B., Timmer, B. J. J., Ahlquist, M. S. G., and Sun, L. (2109). Paired electrocatalytic oxygenation and hydrogenation of organic substrates with water as the oxygen and hydrogen source. Angew. Chem. Int. Ed. 58, 9155-9159.

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